- ● Success rate: TurboKnockout® features 100% guaranteed germline transmission.
- ● Turnaround time: TurboKnockout® features a 6-8 month turnaround time, on par with CRISPR.
- ● loxP restrictions: TurboKnockout® has no size limitations for your floxed region.
- ● Guarantee: TurboKnockout® projects provide 100% money-back guarantee. Most CRISPR projects are not guaranteed and require a non-refundable down payment.
Cyagen’s TurboKnockout® service is the gold standard for generating conditional knockout, conventional knockout, ROSA26 knockin, point mutation knockin, reporter knockin, and humanization mouse models, featuring following innovations, which allows for short turnaround as fast as 6-8 months.
■ Germline guarantee: A super competent ES cell line generates 100% ESC-derived founder mice.
■ Self-deleting selection cassette: Eliminate the need to breed to Flp deleter mice.
■ Germline guarantee: A super competent ES cell line generates 100% ESC-derived founder mice.
■ Self-deleting selection cassette: Eliminate the need to breed to Flp deleter mice.
In the beginning of Fall semester, Cyagen brings you to the best Fall experience with surprising offers.
You can now receive two pairs of homozygous cKO (flox/flox, cre) mice and two pairs of homozygous flox/flox mice at the end of the project. In total, get 8 homozygous mice with a package price at $26,000.
Promotion Period: September 1, 2019 - October 31, 2019 Eligibility: End clients in South Korea, Singapore and New Zealand
| Service | Deliverables | Turnaround | Promotion Price |
|---|---|---|---|
| TurboKnockout® cKO homozygous | 2 pairs of homo (flox/flox,Cre) mice + 2 pairs of homo flox/flox mice |
11 months | $26,000 |
Highlights of TurboKnockout®
TurboKnockout® vs Traditional Gene Targeting
TurboKnockout® gene targeting: 6-8 months
Traditional gene targeting: 10-14 months
How to Order?
service-apac@cyagen.com
86 20-31601779
Request an online quote
We will respond to you in 1-2 business days
Selected Citations of TurboKnockout® Projects
Specific Decrease in B-Cell-Derived Extracellular Vesicles Enhances Post-Chemotherapeutic CD8+ T Cell Responses.
Immunity PMID: 30770248 (2019) IF=19.734
Immunity PMID: 30770248 (2019) IF=19.734
Molecular basis for heat desensitization of TRPV1 ion channels.
Nat Commun 10: 2134 (2019) IF=12.353
Nat Commun 10: 2134 (2019) IF=12.353
Human CPA1 mutation causes digestive enzyme misfolding and chronic pancreatitis in mice.
Gut 68:301-312 (2019) IF=17.016
Gut 68:301-312 (2019) IF=17.016
Parallel circuits from the bed nuclei of stria terminalis to the lateral hypothalamus drive opposing emotional states.
Nat Neurosci 21:1084 (2018) IF=19.912
Nat Neurosci 21:1084 (2018) IF=19.912
Cyagen Transgenic Animal Center
Cyagen Transgenic Animal Center (CTAC) is a specific-pathogen free (SPF) barrier facility that have been AAALAC accredited and OLAW assured. It can house up to 250,000 SPF mice and rats. Cyagen’s breeding service provides reliable, economical, and efficient breeding colonies of mice/rats to support your research needs; allowing you to focus more on your research goals and less on animal care, breeding and colony management issues. We'll make sure you get the mice you need, when you need them, in the exact quantities you specify, and with the health status that you require.
