Knockout Mouse Catalog | Cyagen APAC
Research Trend
How Single-Cell Sequencing Helps Tumor Immunity Research
Single-cell sequencing, capable of characterizing the genome of a single cell, has had a profound impact on the advancement of tumor biology and genetics. Read More ›
Research Trend
How do We Achieve Fast Breeding in Rats?
Fast breeding can help researchers get more positive rodents in a shorter period, so as to rapidly expand the breeding scale according to their needs. Read More ›
Research Trend
Novel Insights into the Animal Models of Diabetes
Many animal models of diabetes have been developed and improved in recent years, among which, the rat and mouse models are the most comprehensively established. Read More ›
Cyagen Newsletter
Preclinical Pharmacological Model of CAR T-Cell Therapy
Carvykti took nearly 4 years from its first clinical trial approval to its final launch, and preclinical research also took significant time and effort. The efficacy and safety evaluation of preclinical drugs is crucial for investigational new drug (IND) application. This article will introduce the selection of pharmacological models centering on preclinical studies of CAR T-cell therapy. Read More ›
Webinar Q&A
Genomically Humanized Mouse Models: Generation and Application in Biomedical Research
Cyagen recently hosted a live webinar covering the generation of genomically humanized mouse models for applications in preclinical research. we offer an extremely brief overview of the presentation and provide Dr. Ouyang’s personal responses to all the questions submitted during the webinar session. Read More ›
Research Trend
What Do You Know about the Quality Control of rAAV Virus?
In recent years, rAAV has become the most important delivery vector of gene therapy. The production and preparation of rAAV is a key and difficult point in gene therapy, because the packaging system and purification method of rAAV will influence the infection efficiency and the expression efficiency of the target gene, and ultimately affect the results. The following article will introduce the necessary quality control (QC) inspection items for rAAV after packaging and production. Read More ›
Research Trend
How AI+Minigene Aids the Research of Aberrant Alternative Splicing
Cyagen has a robust bioinformatics database, which can perform analysis across the whole genome for human genes and genetic disorders, animal models, and cell line models. By combining all available data with our expertise in machine learning and deep neural networks (DNNs) Read More ›
Lentiviral Vectors CGT
How Can Lentiviral Vectors Help CGT Research?
In recent years, lentiviral transduction techniques have been successfully applied to the preparation of CAR-T cells. This article will help you grasp a basic understanding of lentiviral vector preparation and its applications. Read More ›
Eye diseases Humanized Mice Cyagen Newsletter
Fight for Sight - Targeting Genetic Factors of Ophthalmic Diseases
Genes play a highly significant role in the pathogenesis of eye diseases, some of which are highly prevalent in children and adults. Over 60% of cases of childhood blindness are caused by genetic factors (congenital glaucoma, ocular malformations, atrophy of the optic nerve, and retinitis pigmentosa). In adults, genetic factors can also be associated with serious eye diseases, including glaucoma and macular degeneration. Read More ›
Rare Diseases Cyagen Newsletter
SYNGAP1-Related Intellectual Disability (MRD5)
Cyagen assists in the research of rare diseases and provides various mouse/rat models, including the SYNGAP1-related rodent animal models. This article focuses on the gene SYNGAP1 and rare disease MRD5, aiming to help interested researchers continue to build on scientific literature and knowledge. Read More ›