In recent years, rAAV has become the most important delivery vector of gene therapy. The production and preparation of rAAV is a key and difficult point in gene therapy, because the packaging system and purification method of rAAV will influence the infection efficiency and the expression efficiency of the target gene, and ultimately affect the results. The following article will introduce the necessary quality control (QC) inspection items for rAAV after packaging and production.
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Cyagen has a robust bioinformatics database, which can perform analysis across the whole genome for human genes and genetic disorders, animal models, and cell line models. By combining all available data with our expertise in machine learning and deep neural networks (DNNs)
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In recent years, lentiviral transduction techniques have been successfully applied to the preparation of CAR-T cells. This article will help you grasp a basic understanding of lentiviral vector preparation and its applications.
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Genes play a highly significant role in the pathogenesis of eye diseases, some of which are highly prevalent in children and adults. Over 60% of cases of childhood blindness are caused by genetic factors (congenital glaucoma, ocular malformations, atrophy of the optic nerve, and retinitis pigmentosa). In adults, genetic factors can also be associated with serious eye diseases, including glaucoma and macular degeneration.
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Cyagen assists in the research of rare diseases and provides various mouse/rat models, including the SYNGAP1-related rodent animal models. This article focuses on the gene SYNGAP1 and rare disease MRD5, aiming to help interested researchers continue to build on scientific literature and knowledge.
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Cyagen assists in the research of rare diseases and provides various mouse/rat models, including the Cep290 knockout mouse. This article focuses on the gene CEP290 and its related rare diseases, aiming to help interested researchers continue to build on scientific literature and knowledge.
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Read on to explore why rodent groups barber themselves and each other, the ways this may be prevented, and some common questions and answers about this issue.
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In mouse models, what did the researchers find? How does BBS5 knockout/conditional knockout affect mouse phenotype? Please find the answers below, in our Weekly Model research review.
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