Knockout Mouse Catalog | Cyagen APAC
Targeting BBS5 in Bardet-Biedl syndrome (BBS)
Weekly Gene
Targeting BBS5 in Bardet-Biedl syndrome (BBS)
Bardet-Biedl Syndrome (BBS) is a rare genetic disorder with highly variable symptoms which may include retinal degeneration. Read More ›
Inducible Humanized ACE2 Mouse Model For Coronavirus (COVID-19) Research
Research Trend
Inducible Humanized ACE2 Mouse Model For Coronavirus (COVID-19) Research
The newly-developed K18 promoter-driven hACE2-Cre-ERT2 knock-in (hACE2 KI) mouse model with a C57BL/6J background provides an additional platform for continued research. Read More ›
Analyzing the Process of CAR T-Cell Therapy Research
Research Trend
Analyzing the Process of CAR T-Cell Therapy Research
This article focuses on the process of developing CAR T-cell therapy and discusses the importance of each preclinical and clinical stage in the research of CAR T-cell therapy. Read More ›
Why Are Mice Eating Their Babies?
Animal Breeding
Why Are Mice Eating Their Babies?
The topic of today's article is the common problem in mouse breeding of female mice eating pups, also known as infanticide in rodents. Read More ›
Ybx2 Mice and New Research Progress
Weekly Model
Ybx2 Mice and New Research Progress
The YBX2 gene is a germ cell-specific gene, and the phenotype of knockout mice is mainly focused on germ cells. These results indicate that suitable knockout mice are helping to study how the formation of germ cells are influenced by Ybx2. Read More ›
[Weekly Gene] The Secret of YBX2's Regulatory Mechanisms
Weekly Gene
[Weekly Gene] The Secret of YBX2's Regulatory Mechanisms
Although the gene YBX2 is not the direct cause of cancer, it seems to be inextricably linked to cancer, and the latest research shows that high YBX2 expression is unfavorable in prognosis of endometrial cancer. Read More ›
Application of AAV-mediated Gene Therapy in Metabolic Disorders
Research Trend
Application of AAV-mediated Gene Therapy in Metabolic Disorders
The application of recombinant Adeno-Associated Virus (rAAV) drugs in clinical trials of metabolic diseases around the world is mainly concentrated among the following indications Read More ›
Application of Gene Therapy in Mucopolysaccharidosis IVA (MPS IVA) (Part B)
Research Trend
Application of Gene Therapy in Mucopolysaccharidosis IVA (MPS IVA) (Part B)
In Part A, we describe how the Mucopolysaccharidosis IVA (MPS IVA, MPSIVA) rat model is generated. Please see Part B which we explore other promising applications of  AAV9-Galns treatments. Read More ›
Mouse Models of Adamts5 and Drug Development Progress
Weekly Model
Mouse Models of Adamts5 and Drug Development Progress
In the previous article, we shared the diseases related to ADAMTS5 gene mutations, such as osteoarthritis (OA) . Read More ›
Diagnostic Testing of Mouse for Infectious Agents
Animal Breeding
Diagnostic Testing of Mouse for Infectious Agents
As most researchers know, the health of mice may affect the accuracy and reproducibility of experimental data when conducting experiments. Read More ›