Huntington's disease (HD), also known as Huntington's chorea, is a neurodegenerative disease that has a 50% probability of being inherited by children of people living with HD.
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Chronic Kidney Disease (CKD) is characterized by the gradual loss of renal function and progression of renal fibrosis, and is a high-risk factor of end-stage renal disease (ESRD).
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Retinitis pigmentosa (RP) is actually a group of inheritable, chronic eye diseases in humans that often culminate in blindness, with a clinical incidence of 1/4000.
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Leber congenital amaurosis (LCA; OMIM 204000) is a rare inherited retinal dystrophy (IRD) that typically presents with early-onset, potentially blinding visual impairment.
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Single-cell sequencing, capable of characterizing the genome of a single cell, has had a profound impact on the advancement of tumor biology and genetics.
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Fast breeding can help researchers get more positive rodents in a shorter period, so as to rapidly expand the breeding scale according to their needs.
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Many animal models of diabetes have been developed and improved in recent years, among which, the rat and mouse models are the most comprehensively established.
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Carvykti took nearly 4 years from its first clinical trial approval to its final launch, and preclinical research also took significant time and effort. The efficacy and safety evaluation of preclinical drugs is crucial for investigational new drug (IND) application. This article will introduce the selection of pharmacological models centering on preclinical studies of CAR T-cell therapy.
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Cyagen recently hosted a live webinar covering the generation of genomically humanized mouse models for applications in preclinical research. we offer an extremely brief overview of the presentation and provide Dr. Ouyang’s personal responses to all the questions submitted during the webinar session.
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