When establishing a CRISPR/Cas9-based knockout (KO) cell line model, it is important to validate the genetic modifications which have occurred.
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Gene research' s next great example– Mut-Stat3 mice – which has the potential to alter the behavior of or even eliminate autosomal dominant hyper-IgE syndrome (AD-HIES).
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If you want to effectively achieve gene up-regulation or knockdown, constructing an overexpression stable cell line through lentiviral transfection will be your best choice.
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Urotensin II (UTS2/UII) is a potent vasoconstrictor peptide, which signals through a G-protein coupled receptor (GPCR) known as GPR14 or urotensin receptor (UTR).
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Gene therapy aims to treat or cure genetic diseases through the introduction of foreign, normally-functioning genes into target cells to correct or compensate for defective or abnormal genes.
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In future studies, FGF20 may become a hot target for researchers of Parkinson’s disease. Genes perform a variety of functions, and FGF20 is no exception.
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