- ● Traditional natural breeding: The progeny model of a specific genotype is obtained by self-mating and breeding animals constrained by the animal model's normal growth and development conditions as well as sexual cycle. This approach is time-consuming. When time is critical, natural breeding might not meet the researchers’ requirements in speed and quantity.
● IVF Rapid Expansion:
Many offspring of the same age and genotype can be obtained in much less time over
traditional natural breeding. The process includes:
● Superovulation to obtain oocytes;
● In vitro fertilization (IVF) with fresh or frozen sperm;
● Transplanting fertilized egg embryos in the 2-cell period into surrogate mice;
● Obtaining a large number of offspring mice in one generation
- ● Ensure a sufficient number of mice: A large number of colony mice can be obtained in a short time.
- ● Save research time: Our unique in vitro fertilization (IVF) technology can shorten the research cycle by up to 3 months. Usually, it takes 6 weeks for female rats to be sexually mature before they can mate naturally, while superovulated female rats only need 4 weeks. Generally, it takes 3 months to reproduce one generation naturally, but it only takes 1.5 months using IVF technology!
Improve the Consistency of Experimental Data:
Using In Vitro Fertilization (IVF) for rapid expansion is equivalent to the simultaneous mating of male mice and many female mice in vitro, which ensures the consistency of the birth age. This reduces the experimental deviation caused by the different ages of the mice, and the experimental data will be more dependable.
Improve The Quality of Mice: IVF is a good method for male mice that can not reproduce naturally due to fertility issues; with IVF, we can obtain animals with a higher level of health. Requires only a few males to expand the colony.