Knockout Mouse Catalog | Cyagen APAC
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15th Anniversary Celebration Lucky Draw Challenge Win up to $2,000 OFF on Animal Models

Since the establishment in 2005, Cyagen has become one of the world's leading provider of custom mouse and rat models, which successfully delivered over 50,000 custom animal models to researchers across the globe. To celebrate the 15th birthday of Cyagen, We here invite you to get involved in our special Lucky Draw Challenge - Cyagen now provide ready-to-use gene knockout (KO) and conditional knockout (cKO) mice from Cyagen AI Knockout Mouse Model eBank, as well as diversified customization services (both mouse and rat are available) including KO/cKO, KI/cKI, Point Mutation, Transgenic, with rapid turnaround and competitive prices.

There are limited quantities of our exclusive prizes available – up to $2,000 OFF - Join before they disappear!

Cyagen Lucky Draw Challenge
Terms and Conditions

Promotion Period:

Apply for a Lucky Draw voucher before January 31st, 2021.

Lucky Draw Voucher Details:

Vouchers are valid for use until March 31st, 2021. Non-refundable, non-transferable, and valid for a single transaction only. It has no cash value and cannot be exchanged for cash. Not valid in conjunction with other special promotions. Other discounts cannot be applied while using any voucher.

Limitations on Voucher Usage:

a) Credits worth $200 and $500 can be applied as a general voucher for all catalog model orders;
b) $1,000 and $2,000 voucher is appliable to cKO orders from our catalog and other model customizations (including but not limited to cryopreserved sperms, custom models, live mice).


End clients in the APAC region, excluding Japan. Each participating customer is limited to one (1) entry. If you need immediate assistance, please call 86 20-31601779 or email

Cyagen AI Knock-Out Mouse Model eBank
Advantages of Cyagen AI Knockout Mouse Model eBank
 No risk of failure: Our catalog features gene knockout mice that have been strictly analyzed to ensure 100% positive knockout.
 Professional Technical Support
 AAALAC-Accredited and OLAW Assured
 Deliverables: as fast as 3 month
Reduced paperwork: Inquire online to place an order, one click to get detailed information and modeling guidance, backed by a powerful database.
 100% pure B6 background eliminates need for backcrossing – most repositories have mixed backgrounds
 Inexpensive: Cost of catalog lines cannot be beaten by any model generation approach
TurboKnockout® - Proprietary Method for Accelerated Generation of Precise Mouse Models

Cyagen's Proprietary Method for Accelerated Generation of Precise Mouse Models

Our proprietary TurboKnockout® gene targeting method can provide you with conditional knockout, reporter knockin and humanization mouse models as fast as 6-8 months. This proprietary gene targeting method is enabled by two innovations:

Eliminates the unpredictability of germline transmission (GLT) with our super competent ESC line that generates 100% ESC-derived founder mice rather than chimeras.

Self-removing selection cassette circumvents the need to breed to Flp deleter mice.

These innovations eliminate at least two generations of breeding, shortening production time by 4-6 months as compared to the industry standard.


Faster Turnaround with Turboknockout®

TurboKnockout® gene targeting: 6-8 months

Traditional gene targeting: 10-14 months


Highlights of TurboKnockout® Gene Targeting

No patent risk: Technology of choice for drug development projects
Success rate: 100% guaranteed germline transmission (GLT)
Turnaround time: Founders as fast as 6-8 months
Large fragment knockin size: Knockin (KI) fragment size up to 200 kb
Limitless loxP: No size limitations for your floxed region
100% Money-Back Guarantee on TurboKnockout® projects




Donor Strains Mouse: C57BL/6, BALB/c


TurboKnockout® for BALB/c Drug Development Models

BALB/c is a laboratory-bred, albino strain of the house mouse, characterized by its immunodeficiency and extreme susceptibility to carcinogens. BALB/c mice are among the most widely used mouse strains across oncology, immunology, nuclear medicine research, and are often the first option for animal experimentation models in new drug development projects.

TurboKnockout® is based on traditional embryonic stem cell (ESC) targeting techniques, which can be used for complex genetic modification projects to provide BALB/c mouse models and is the technology of choice among our clients performing drug development projects.

Cyagen CRISPR-Pro Technology - Capabilities for Mouse & Rat Models

Engineered nuclease-mediated genome editing (especially CRISPR/Cas9) is an emerging technology which can serve as an alternative to the conventional, ES cell homologous recombination-based knockout (KO) animal generation. These methods have enabled the generation of custom mouse and rat models with genetic knockouts, point mutations, and large fragment knockins (LFKIs).

Cyagen's CRISPR-based Rapid Knockout services use accelerated methodology that provides conventional knockout, reporter knockin, and humanization founder animals in as fast as 3 months.



Donor Strain Information:

Mouse strains: C57BL/6, FVB
Rat strains: Sprague-Dawley (SD), Long Evans
Note: Other strains available upon request.

Transgenic Capabilities for Animal Models
Items Regular Transgenic PiggyBac Transgenic Rosa26 Targeted Transgenic
Integration Random, multicopy integration Random, single copy per integration site Single copy transgene targeted to Rosa26 safe harbor locus
Vector construction Plasmid or BAC Plasmid or BAC CRISPR or TurboKnockout®
Expression pattern Variable More consistent Most consistent
Endogenous effects Can disrupt endogenous genes Less likely to disrupt endogenous genes Safe harbor locus
Donor Strain Information Mouse strains: C57BL/6, FVB
Rat strains: Sprague-Dawley (SD), Long Evans
Note: Other strains available upon request.


PiggyBac transgenic services can deliver single-copy transgenic animals with more consistent expression of your transgene. This proprietary transgenic method has the following advantages over other transgenic approaches:

Single-copy integration: Avoids potential gene silencing from multiple copies
Defined region of integration: No loss of transgene sequence (TTAA, transcription unit)
Reliability: More consistent expression pattern compared to plasmid based transgenics
Economical: Cost and turnaround time comparable to plasmid based transgenics

Cyagen Model Generation Expertise
15+ years' experience
in custom animal model
50,000+ animal models
generated and delivered
4,500+ citations in
SCI journals for our
3,000+ university and
company partners
Customer Testimonials

"We generated a mouse knockout model using Cyagen’s TurboKnockout® technology. Cyagen's team was on time with milestones, provided constant updates on the project and delivered animals as promised. It was such a pleasure working with Cyagen that we decided to outsource the production of other animal models to them."

-- Maximiliano D’Angelo, Sanford Burnham Prebys Medical Discovery Institute