Main Topics: 

• Strategies and methodsof different gene-editing technologies
• Generation of transgenic mice by pronuclear injection (PNI)
• Homologous recombination in embryonic stem (ES) cells
• Comparison of Gene Targeting (GT) and pronuclear injection (PNI)
• Nuclease-induced genome editing – Applications of CRISPR
• Pros and cons of CRISPR/Cas-mediated Genome Editing
• TurboKnockout^® - Accelerating ES Cell Gene Targeting

Lecturer

Dr. Marvin Ouyang

Executive Vice President and Chief Scientific Officer

Dr. Marvin Ouyang has been dedicated to the development of genetically engineered rodent models for the past 20 years, developing hundreds of transgenic and KO/KI mouse/rat models for biomedical research and drug development. Previously, he served as the senior scientist of Oklahoma Medical Research Foundation (OMRF), a scientist for U.S.-based Thios Pharmaceuticals , and worked for Taconic Biosciences as the leader of the Molecular Biology Department. So far, he has published many papers in high-impact academic journals such as PNAS and JBC. Technical services developed by Dr. Ouyang have been directly cited hundreds of times by top international journals, including Nature.