The World Health Organization (WHO) announced the reclassification of the COVID-19 outbreak as a global pandemic on March 11, 2020. With the rapid spread of the disease across the globe, countries worldwide have joined the war against the SARS-CoV-2 virus, for which, early prevention, control, and treatment may provide valuable tools against the pandemic. Currently, research and development of treatment is of the highest priority. In order to effectively address COVID-19 as a public health threat, we need an in-depth understanding of its infection and immune mechanisms.
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After the emergence of the novel coronavirus, SARS-CoV-2, a war against the resulting disease, COVID-19, and its sequelae – severe respiratory illness and pneumonia - has been rapidly and extensively introduced in China. In our fight against the virus and COVID-19, researchers have studied the SARS-CoV-2 virus itself and its host receptor, ACE2, from the aspects of epidemiology, pathology, virus traceability, prevention, and control measures.
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With the gradual improvement of the COVID-19 situation in China in the past few days, along with a worsening situation across many regions, research on vaccines and related antiviral drugs has become a key issue for most people both inside and outside the life science research industry.
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Since COVID-19 poses a significant threat to public health and also represents a challenge for antiviral drug development and administration globally, current efforts focus on prevention and control while accelerating the research on the SARS-CoV-2 coronavirus, which has caused the outbreak of COVID-19. So far, studies on the epidemiological and clinical characteristics of this illness is still growing, but there is significant anecdotal evidence of value.
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The novel coronavirus, now officially designated as SARS-CoV-2, was first identified in Wuhan, Hubei Province, China in December of 2019. This virus has led to an outbreak of COVID-19 (Coronavirus Disease in 2019), which is associated with acute respiratory illness and infection, as is common for diseases caused by the coronavirus family.
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At present, the prevention and treatment of coronavirus is the most urgent issue for scientific and medical research. In addition to the ACE2 host receptor target that is being highly focused on, what other targets deserve the attention of current coronavirus researchers? Herein, experts from Cyagen investigate the lesser-known targets that are pertinent to coronavirus research, aiming to provide some helpful references to guide scientific researchers.
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At the end of 2019, a large-scale illness broke out from Wuhan, Hubei Province - a central province of China. The virus that cased this illness could enter the respiratory tract through droplets - moreover, the increasingly busy traffic conditions and travel around the holiday season made the virus spread extremely rapidly.
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The recent emergence of Coronavirus Disease in 2019 (COVID-19), caused by infection by SARS-CoV-2, has put the world on high alert. People are concerned about how soon drugs and vaccines will be available after the isolation of virus strains and the completion of sequencing and comparative analysis.
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