Knockout Mouse Catalog | Cyagen APAC

Despite the effects of COVID-19 on global business, we are operating at 100% proficiency - providing uninterrupted production and technical support to ensure that your research continues. We will continue serving your model generation, cloning, and virus packaging needs with the same high quality and fast turnaround as before the outbreak. Cyagen has established strong partnerships worldwide, improved our rigorous safety standards, and maintained full operational efficiency to ensure continuity in research operations for all our clients throughout this critical time.

The experts at Cyagen remain available to support all your research needs, while continuing development of complimentary resources for those seeking accurate animal models for their COVID-19 studies. Below, we have collected some of our key responses that aim to support COVID-19 research and ensure the stability of all ongoing scientific studies.

COVID-19 Research: Resources and Support

We understand that institutions worldwide are adapting to new measures towards the prevention and control of COVID-19 – all of our project timelines may be adapted to meet your needs. As a leading provider of animal models with a strong basis in social responsibility – Cyagen’s research and development (R&D) team continues to prioritize development of both animal models and technical resources catered to the global COVID-19 research initiative. 

How can Cyagen help you?

  • Targeting strategies and quotes provided within 48 hours of request
  • Free project consultation from our scientists
  • Exclusive price matching for competitor quotes
  • Complimentary support for your research funding application

For more information about what we can offer for COVID-19 research, technical resources for coronavirus models, and how Cyagen’s animal model experts can support your study, visit our newest campaign page:

>> Indispensable Mouse Models for Coronavirus Research


Coronavirus Mouse Models  – Knockout (KO), Knockin (KI), Humanized Mice

Cyagen is prioritizing production of coronavirus mouse models to support research on COVID-19, the disease caused by SARS-CoV-2 virus. We have opened orders for mouse models at multiple hot targets - ACE2, DPP4, TMPRSS2, CD147 and so on at special offer.

For humanized models, knockout models, Rosa26 knockin mouse models of ACE2 and DPP4 on C57BL/6 mouse strains, the exclusive sales prices are as below:

ACE2 / DPP4 Service Deliverable Promotion Price(USD/Strain)
Knockout Mice ≧3 F1 Heterozygotes 3,599
Humanized Mice 4 F1 Heterozygotes 5,000
Knockin Mice (Rosa26) 4 F1 Heterozygotes 6,000

Note: Cyagen can also offer mouse models in BALB/c background, the above prices are for end clients in South Korea only. Other regions, please contact us for more information.

For more information, visit here: Expedite Your COVID-19 Research Efforts 


Coronavirus Research in Review: Genetic Targets, Mouse Models, and More

Recent publications have focused on the importance of the ACE2 host receptor implicated in SARS-CoV-2 infection, but there are numerous other targets known to play key roles in the pathology of closely-related viruses. In our newest Technical Bulletins, we review the variety of targets pertinent to research efforts against the COVID-19 outbreak, including:

  • ACE2 (Angiotensin-converting enzyme 2)
  • DPP4 (Dipeptidyl peptidase-4)
  • APN (Aminopeptidase N)
  • TMPRSS2 (Transmembrane Serine Protease 2)
  • ADAM17 (ADAM Metallopeptidase Domain 17)
  • LY6E (Lymphocyte Antigen 6 Complex, Locus E)
  • SIGN/CD209L (Cluster of Differentiation 209)
  • CD147 (Cluster of Differentiation 147)
  • DHODH (Dihydroorotate Dehydrogenase)
  • ... and more!

Learn more about the above targets’ roles in coronavirus infections by visiting our Technical Bulletin, which provides a complete listing of our freely-available scientific reviews and resources to support COVID-19 research:

>>  Cyagen Thematic Compilation of Coronavirus: everything you need to know about the Novel Coronavirus (COVID-19)


Virtual Consultations for Custom Animal Models

With the emergence of the novel coronavirus (SARS-CoV-2), the meetings, shows, and conferences that allow us to interface with customers in person have been canceled for the foreseeable future. Cyagen specialist team and its international partners are working together to flatten the curve. To better support your research needs, we are readily-available for virtual consultations to discuss custom mouse model design!

Our 3-step process will not only help you get moving on a project, but also support your preparations to include your custom model in a grant application:

  1. Initial Consultation: 30 Minute Teleconference
    • Design capabilities include (but are not limited to): TurboKnockout®, CRISPR/Cas9, Constitutive KO, Point Mutation, Conditional Knockout, PiggyBac Transgenic, Targeted Transgenic (ROSA26, H11, Conditional Overexpression), Large Fragment Knockin
  2. After Teleconference, the Model Design Specialist will provide the following via email within 2-3 business days:
    • Targeting strategy – complete with details and figures to use in funding requests and grant applications
    • Price Quotation
    • Letter of Support (for funding/grant applications)
  3. Second Consultation: 30-60 Minute Teleconference
    • Step-by-Step review of Targeting Strategy with Model Design Specialist

With the current social distancing measures that have been put in place, we understand that many labs are reducing to critical staff only. If you're worried about maintaining your live colonies, our team is also available to discuss cryopreservation options to protect your valued genetically engineered models until you are ready for them.


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