In mouse models, what did the researchers find? How does BBS5 knockout/conditional knockout affect mouse phenotype? Please find the answers below, in our Weekly Model research review.
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The YBX2 gene is a germ cell-specific gene, and the phenotype of knockout mice is mainly focused on germ cells. These results indicate that suitable knockout mice are helping to study how the formation of germ cells are influenced by Ybx2.
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In the previous article, we shared some diseases related to MARCHF2 (a.k.a. MARCH2). To this end, we introduce gene research' s next great example of this – Marchf2 knockout mice.
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To study the mechanisms that are largely unknown, researchers use gene knockout or down-regulation to regulate the expression of mouse Inpp5e gene.
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Gene research' s next great example– Mut-Stat3 mice – which has the potential to alter the behavior of or even eliminate autosomal dominant hyper-IgE syndrome (AD-HIES).
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In future studies, FGF20 may become a hot target for researchers of Parkinson’s disease. Genes perform a variety of functions, and FGF20 is no exception.
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The establishment of these mouse models is helpful for research on the function of the hnRNP C1 and C2 proteins and the regulatory expression of the splicing factor hnRNP C. Insight into new research results
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