Knockout Mouse Catalog | Cyagen APAC

From January through June of 2020, Cyagen received over 70 citations for our animal models, contributing to many advances across research fields. We have put together the below list of articles from high impact factor (IF) journals to provide insights into a variety of mouse model types, gene targets, research applications, and some of the most recent developments shown in scientific literature.

The following publications demonstrate the use of genetically modified mouse models across a range of human disease research, including atherosclerosis, inflammatory disorders, cardiovascular disease, oncology, metabolism, and virology. All citations listed feature gene targets included among our ready-to-use Cyagen Knockout Catalog Models – as fast as 2 weeks!

Cyagen Knockout Catalog Models - Featured 2020 Publications

Mouse Model Type Used

Gene Target

Research Applications

Knockout Catalog Model Link


Journal Information

Knockin (KI)



Ldlr KO Mouse

In Vivo AAV-CRISPR/Cas9-Mediated Gene Editing Ameliorates Atherosclerosis in Familial Hypercholesterolemia.


DOI: 10.1161/CIRCULATIONAHA.119.042476

Knockout (KO)



Dapp1 KO Mouse

Melatonin Enhances Thrombopoiesis Through ERK1/2 and Akt Activation Orchestrated by Dual Adaptor for Phosphotyrosine and 3-phosphoinositides

Journal of Pineal Research

DOI: 10.1111/jpi.12637



Drd5 KO Mouse

Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation

Molecular Cell

DOI: 10.1016/j.molcel.2020.01.022

Conditional Knockout (cKO)



Steap4 KO Mouse

Inflammation Mobilizes Copper Metabolism to Promote Colon Tumorigenesis via an IL-17-STEAP4-XIAP Axis

Nature Communications

DOI: 10.1038/s41467-020-14698-y



Raly KO Mouse

Collaborative Interactions of Heterogenous Ribonucleoproteins Contribute to Transcriptional Regulation of Sterol Metabolism in Mice

Nature Communications

DOI: 10.1038/s41467-020-14711-4



Rbck1 KO Mouse

Regulation of the Linear Ubiquitination of STAT1 Controls Antiviral Interferon Signaling

Nature Communications

DOI: 10.1038/s41467-020-14948-z


Save Up to $6,000 on Knockout Catalog Orders – Win a Free cKO Models and Breeding Coupon!

Now through August 31st, order any ready-to-use knockout (KO) strains from the Cyagen AI Knockout Mouse Model eBank to receive free cKO mice of the same gene and additional breeding incentives – providing a total savings of $6,000.

Learn more about this offer by visiting the promotional page: Win a KO + Free cKO Model, $6,000 saved up! 


About Cyagen Biosciences

Genetically engineered animals remain essential for gaining proper understanding of human disease mechanisms and play an important role in a variety of research areas. Since our founding in 2005, Cyagen has been cited in over 4,000 publications – all of which are available as a searchable list. 

For a complimentary consultations and quotes, please call 86 20-31601779 or email to get in touch with our model generation experts.



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