Transwell Invasion

Transwell invasion is a commonly used testing method for cell migration. Cell migration is also called cell crawling, cell movement, or cell motility. It refers to the movement of cells after receiving a migration signal or sensing the gradient of certain substances. Cell migration is one of the basic functions of normal cells, the physiological process of normal growth and development of the body, and a form of movement common in living cells.

 

Experimental Principal:

The upper chamber is filled with the upper culture fluid medium, the lower chamber contains with the lower culture medium, and the upper and lower culture medium were separated by polycarbonate membrane. The cells are planted in the upper chamber. Due to the permeability of the polycarbonate membrane, the components in the lower culture medium could affect the cells in the upper chamber. This is used to study the how growth and movement of cells may be influenced by the components in the lower culture medium.

Reference:

https://www.protocols.io/view/look-for-cell-invasion-experiment-how-about-follow-br6nm9de.html

 

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