Herein, we review the background of CAR T cell therapy in solid tumor treatment, common research targets, CAR T optimization strategy, and clinical research progress.
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This article will discuss the disease-causing gene CFTR, its 6 types of mutations, and the application of the CFTR mouse model in research.
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In this article, we will further demystify HD, introducing its causative genes, other treatments, and the application of related animal models.
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Retinitis pigmentosa (RP) is actually a group of inheritable, chronic eye diseases in humans that often culminate in blindness, with a clinical incidence of 1/4000.
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Leber congenital amaurosis (LCA; OMIM 204000) is a rare inherited retinal dystrophy (IRD) that typically presents with early-onset, potentially blinding visual impairment.
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Single-cell sequencing, capable of characterizing the genome of a single cell, has had a profound impact on the advancement of tumor biology and genetics.
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Fast breeding can help researchers get more positive rodents in a shorter period, so as to rapidly expand the breeding scale according to their needs.
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Many animal models of diabetes have been developed and improved in recent years, among which, the rat and mouse models are the most comprehensively established.
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